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• 產(chǎn)品描述： Reboxetine mesylate (FCE20124 mesylate) is a potent, selective, and specific noradrenaline reuptake inhibitor (NARI) for the research of depression. Reboxetine mesylate inhibits the uptake of norepinephrine, with a Ki of 8 nM

• 靶點(diǎn)： Ki: 8 nM (NA reuptake);AdrenergicReceptor;?Norepinephrine

• 體內(nèi)研究：
  Reboxetine mesylate (30 mg/kg; i.p.) significantly decreases the immobility time in the mice depression models

• 參考文獻(xiàn)：
  1. Wong, E.H., et al., Reboxetine: a pharmacologically potent, selective, and specific norepinephrine reuptake inhibitor. Biol Psychiatry, 2000. 47(9): p. 818-29. 2. Versiani, M., et al., Reboxetine, a unique selective NRI, prevents relapse and recurrence in long-term treatment of major depressive disorder. J Clin Psychiatry, 1999. 60(6): p. 400-6. 3. M Leskiewicz, et al. Antidepressants attenuate the dexamethasone-induced decrease in viability and proliferation of human neuroblastoma SH-SY5Y cells: a involvement of extracellular regulated kinase (ERK1/2). Neurochem Int. 2013 Nov;63(5):354-62.

• 溶解性： DMSO  :  125  mg/mL  (305.25  mM;  Need  ultrasonic)    H2O  :  50  mg/mL  (122.10  mM;  Need  ultrasonic)

• 保存條件： 2-8℃

• 配置溶液濃度參考：
  

  	1mg	5mg	10mg
  1 mM	2.442 ml	12.21 ml	24.42 ml
  5 mM	0.488 ml	2.442 ml	4.884 ml
  10 mM	0.244 ml	1.221 ml	2.442 ml
  50 mM	0.049 ml	0.244 ml	0.488 ml

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

輸入產(chǎn)品批號(hào)：

本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *