• 介紹：

  Dexamethasone是一種糖皮質(zhì)激素受體激動(dòng)劑和一種 IL 受體調(diào)節(jié)劑。在脂多糖誘導(dǎo)的巨噬細(xì)胞炎癥反應(yīng)中，它抑制含有炎性 microRNA-155 的外泌體的產(chǎn)生。

• 熔點(diǎn)： 255-264°C

• 沸點(diǎn)： 568.2oC at 760 mmHg

• 比旋光度： 75 o (c=1, dioxane)

• 外觀： 白色結(jié)晶固體

• 溶解性： DMSO:73  mg/mL  (186  mM)
  Ethanol:6  mg/mL  (15.28  mM)

• 敏感性： 對(duì)光和空氣敏感

• 儲(chǔ)存條件： 2-8℃

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

• 36. [3.8] Guoping Cai et al."NLRP3 blockade by MCC950 suppressed osteoclastogenesis via NF-κB/c-Fos/NFATc1 signal pathway and alleviated bone loss in diabetes mellitus."MOLECULAR AND CELLULAR ENDOCRINOLOGY.2024 Dec;594:112382

• 35. [6] Mengting Li et al."Design, synthesis, and biological evaluation of oridonin derivatives as novel NLRP3 inflammasome inhibitors for the treatment of acute lung injury."EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY.2024 Aug;:116760

• 34. [2.9] Jingjing Yan et al."The natural sesquiterpene lactone inulicin suppresses the production of pro-inflammatory mediators via inhibiting NF-κB and AP-1 pathways in LPS-activated macrophages."IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY.

• 33. [1.3] Jing-Yu Zhang et al."Bioactive prenylated c6–c3 derivatives from the roots of Illicium brevistylum."JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH.

• 32. [4.7] Wenjing Li et al."Safflower yellow in Carthami Flos is responsible for Xuebijing Injection-induced immediate hypersensitivity reaction through activating complement C3."Chinese Herbal Medicines.2024 Jun;:

• 31. [IF=3.1] Meng Yan et al."Diammonium Glycyrrhizinate Inhibited Inflammatory Response and Modulated Serum Metabolism in Poly(I:C)-induced Pneumonia Model Mice."SHOCK".2024 Mar;:10.1097/SHK.0000000000002353

• 30. [IF=5.6] Rong Xu et al."Extracellular ATP contributes to the reactive oxygen species burst and exaggerated mitochondrial damage in D-galactosamine and lipopolysaccharide-induced fulminant hepatitis."INTERNATIONAL IMMUNOPHARMACOLOGY".2024 Mar;130:111680

• 29. [IF=1.8] Xiaojuan Li et al."Peimine Alleviated Bleomycin-Induced Pulmonary Fibrosis in Mice Through Reducing Epithelial-Mesenchymal Transition, Inflammation and Oxidative Stress and Regulating Host Metabolism."Natural Product Communications.;():

• 28. [IF=7.9] Xin-yun-xi He et al."Orcinol glucoside targeted p38 as an agonist to promote osteogenesis and protect glucocorticoid-induced osteoporosis."PHYTOMEDICINE.2023 Oct;119:154953

• 27. [4.004] Wen-Rui Li et al."Bergamotane-type sesquiterpenes from the leaves and twigs of Illicium oligandrum and their anti-inflammatory activities."PHYTOCHEMISTRY.2023 May;209:113617

• 26. [6.317] Kun Wang et al."Mechanic study of salidroside on ovalbumin-induced asthmatic model mice based on untargeted metabolomics analysis."Food & Function.2022 Nov;:

• 25. [IF=2.98] Chen Rui et al."Maternal obesity induces liver lipid accumulation of offspring through the lncRNA Lockd/mTOR autophagy pathway."MOLECULAR GENETICS AND GENOMICS.2022 Jun;:1-11

• 24. [IF=3.922] Fengling Wang et al."Activation of Pregnane X Receptor–Cytochrome P450s Axis: A Possible Reason for the Enhanced Accelerated Blood Clearance Phenomenon of PEGylated Liposomes In Vivo."Drug Metab Dispos. 2019 Aug;47(8):785-793

• 23. [IF=4.05] Zhi-Yuan Wu et al."Anti-inflammatory Diterpenoids from the Root Bark of Acanthopanax gracilistylus."J Nat Prod. 2014;77(11):2342–2351

• 22. Mengqiu Lu, Haizhen Liang, Pengfei Tu, Yong Jiang. Pharmacodynamic comparison of two different source plants of Murrayae Folium et Cacumen[J]. Journal of Chinese Pharmaceutical Sciences, 2021, 30(1): 49-57.DOI: 10.5246/jcps.2021.01.005

• 21. Yanqiu, et al. "Comparative two-dimensional HepG2 and L02/ cell membrane chromatography/ C18/ time-of-flight mass spectrometry for screening selective anti-hepatoma components from Scutellariae Radix. " Journal of pharmaceutical and biomedical analysis 164

• 20. Wu, Zhi-Yuan, et al. "Anti-inflammatory diterpenoids from the root bark of Acanthopanax gracilistylus." Journal of natural products 77.11 (2014): 2342-2351.http://pubs.acs.org/page/copyright/permissions.html

• 19. Wu, Zhi-Yuan, et al. "Anti-inflammatory diterpenoids from the root bark of Acanthopanax gracilistylus." Journal of natural products 77.11 (2014): 2342-2351.124.17.89.23

• 18. Xu, Ye, et al. "CYP3A4 inducer and inhibitor strongly affect the pharmacokinetics of triptolide and its derivative in rats." Acta Pharmacologica Sinica 39.8 (2018): 1386-1392.https://doi.org/10.1038/aps.2017.170

• 17. Gu, Yanqiu, et al. "Development of 3-mercaptopropyltrimethoxysilane (MPTS)-modified bone marrow mononuclear cell membrane chromatography for screening anti-osteoporosis components from Scutellariae Radix." Acta Pharmaceutica Sinica B 10.10 (2020): 1856-186

• 16. 柏永全,史睿,茹凝玉,馬麗蓉,王芙蓉,王文文,陳果.雷公藤紅素緩解刀豆蛋白A誘導(dǎo)的小鼠急性肝損傷作用及其機(jī)制[J].河南大學(xué)學(xué)報(bào)(自然科學(xué)版),2020,50(05):551-559.

• 15. 王長(zhǎng)華,王鑫,沈佚葳,劉凱.紫草素對(duì)濕疹小鼠的治療作用及機(jī)制研究[J].中國(guó)藥師,2021,24(03):456-461.

• 14. 王文文,柏永全,鄧樂(lè)樂(lè),宋貞潔,陳果,盧茲凡,翟東昇.水蘇堿對(duì)葡聚糖硫酸鈉誘導(dǎo)的炎性腸病的保護(hù)作用及其機(jī)制[J].河南大學(xué)學(xué)報(bào)(自然科學(xué)版),2021,51(01):48-57.

• 13. 胡蔚,李嵐.枇杷葉提取物對(duì)卵清蛋白誘導(dǎo)的哮喘小鼠氣道炎癥和氣道重塑的影響[J].中國(guó)現(xiàn)代應(yīng)用藥學(xué),2021,38(01):20-27.

• 12. 肖衛(wèi)棉,查旭山,王友發(fā).丹皮酚對(duì)濕疹模型小鼠SP、NK1R表達(dá)及肥大細(xì)胞活化的影響[J].天津醫(yī)藥,2020,48(09):824-828+913-914.

• 11. 苗延青,尤靜,薛鵬燕.柴胡、黃芩、甘草、葛根四種藥物顆粒劑與水煎劑抗炎鎮(zhèn)痛作用比較[J].醫(yī)學(xué)信息,2020,33(21):73-75.

• 10. 張東博, 王征, 梁艷妮,等. 青花椒根皮中1個(gè)新的香豆素類(lèi)化合物[J]. 中草藥 2019年50卷12期, 2798-2801頁(yè), ISTIC PKU CSCD CA, 2019.

• 9. 徐葉,杜江波,馮慧瑾,左建平,許紅濤,李援朝,鐘大放.雷公藤甲素衍生物雷騰舒的體外代謝研究[J].藥學(xué)學(xué)報(bào),2019,54(08):1484-1492.

• 8. 黃洋, 邵慧凱, 李康,等. 小葉榕葉抗炎成分分析及活性評(píng)價(jià)[J]. 中成藥, 2014(06):1227-1233.

• 7. 黃洋,李康,邵慧凱,劉盛權(quán).小葉榕葉對(duì)LPS誘導(dǎo)的RAW264.7巨噬細(xì)胞NO和TNF-α的影響[J].中藥新藥與臨床藥理,2014,25(02):124-127.

• 6. 葛瑜,繆華.宣白承氣湯調(diào)控sirt1/FOXO1通路對(duì)脂多糖致大鼠急性肺損傷的影響[J].四川中醫(yī),2020,38(07):52-56.

• 5. 劉珊珊, 向彬, 郭營(yíng)營(yíng),等. 天麻成分對(duì)羥基苯甲醛抗炎作用及機(jī)制研究[J]. 中國(guó)民族民間醫(yī)藥, 2016(9).

• 4. 李艷, 蔣石, 郭營(yíng)營(yíng),等. 天麻成分對(duì)羥基苯甲醇抗實(shí)驗(yàn)性腦血栓形成及抗炎作用研究[J]. 昆明醫(yī)科大學(xué)學(xué)報(bào), 2015, 036(001):P.28-31.

• 3. 白隆博, 馬逍遙, 常念偉,等. 基于整合網(wǎng)絡(luò)藥理學(xué)和化學(xué)物質(zhì)組學(xué)的燈臺(tái)葉片的抗炎作用機(jī)制研究[J]. 中草藥, 2018, v.49;No.627(16):139-145.

• 2. 葛淑瑜, 李嵐, 孫萍萍. 桑白皮總黃酮對(duì)哮喘小鼠氣道炎癥反應(yīng)的保護(hù)作用. 溫州醫(yī)科大學(xué)學(xué)報(bào).

• 1. 畢冉冉 白睿 劉志強(qiáng) 劉惠亮.人誘導(dǎo)多能干細(xì)胞來(lái)源間充質(zhì)干細(xì)胞與骨髓間充質(zhì)干細(xì)胞的生物學(xué)性狀比較[J].軍事醫(yī)學(xué) 2018 42(12):941-948.

輸入產(chǎn)品批號(hào)：

本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *