• 介紹：

   Tigecycline (GAR-936) 是一種廣譜的甘氨酰環(huán)素抗生素。Tigecycline 對(duì) E. coli (MG1655 菌株) 的平均抑制濃度 (MIC) 約為 125 ng/ mL。對(duì) Acinetobacter baumannii (A. baumannii) 的 MIC₅₀ 和 MIC₉₀ 分別為 1 和 2 mg/L。

• 熔點(diǎn)： 164-166°C

• 沸點(diǎn)： 890.922°C at 760 mmHg

• 外觀： Orange powder

• 溶解性： DMSO  :  150  mg/mL  (256.13  mM;  Need  ultrasonic)
  
  H2O  :  8.33  mg/mL  (14.22  mM;  ultrasonic  and  warming  and  heat  to  60°C)

• 儲(chǔ)存條件： 2-8℃

• 注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

• 8. [5] Fulei Li et al."Inosine reverses multidrug resistance in Gram-negative bacteria carrying mobilized RND-type efflux pump gene cluster tmexCD-toprJ."mSystems.

• 7. [IF=6.4] Yang# Jindian et al."Repurposing harmaline as a novel approach to reverse tmexCD1-toprJ1-mediated tigecycline resistance against klebsiella pneumoniae infections."Microbial Cell Factories".2024 Dec;23(1):1-17

• 6. [IF=7.9] Xia Xiao et al."Gramine sensitizes Klebsiella pneumoniae to tigecycline killing."PHYTOMEDICINE".2024 Feb;:155421

• 5. [IF=3.9] Jie Wu et al."In vitro Antimicrobial Activity and Dose Optimization of Eravacycline and Other Tetracycline Derivatives Against Levofloxacin-Non-Susceptible and/or Trimethoprim-Sulfamethoxazole-Resistant Stenotrophomonas maltophilia."Infection and Drug Resi

• 4. [5.988] Wei Lu et al."An LC-MS/MS method for the simultaneous determination of 18 antibacterial drugs in human plasma and its application in therapeutic drug monitoring."Frontiers in Pharmacology.2022 Nov 8;13:1044234

• 3. [IF=5.882] Zi-Jian Zheng et al."MALDI-TOF MS for rapid detection and differentiation between Tet(X)-producers and non-Tet(X)-producing tetracycline-resistant Gram-negative bacteria."Virulence. 2022;13(1):77-88

• 2. [IF=4.003] Hui Zhang et al.In vitro and in vivo Activity of Combinations of Polymyxin B with Other Antimicrobials Against Carbapenem-Resistant Acinetobacter baumannii.Infect Drug Resist. 2021 Nov;14:4657-4666

• 1. 馬霖 孫加琳 李恩澤 等. LC-MS/MS法同時(shí)測(cè)定人血漿中伏立康唑和替加環(huán)素的濃度[J]. 中國(guó)臨床藥理學(xué)雜志 2019 035(024):3237-3240.

輸入產(chǎn)品批號(hào)：

本計(jì)算器可幫助您計(jì)算出特定溶液中溶質(zhì)的質(zhì)量、溶液濃度和體積之間的關(guān)系，公式為：

質(zhì)量 (mg) = 濃度 (mM) x 體積 (mL) x 分子摩爾量 (g/mol)

• pg ng μg mg g kg =
  fM pM nM μM mM M *
  nL μL mL L *